I heard an interview with a world-class guitarist (forgot who, but not classical) where he said he bends every (presumably fretted) note; I wonder whether this is to play non-even temperaments from an even-tempered fret spacing.
Basically, while studying temperament is interesting, the reality is it rarely causes practical issues. Most pianos are tuned with equal temperament, which is good enough and almost every other western instrument has enough flexibility to adjust "on the fly."