If my C is 1000x faster and saves me 60 seconds every time I run the program, but takes an extra 2 days to write initially, and the program is seeing lots of edits meaning that on average I have to wait 2 minutes for it to compile then I am MUCH better off with the slower MATLAB until I am running the same thing a few thousand times.
Plus there is the fact that I can look at HN while a slightly slower program is running, so I win both ways.