The Systems Programming side of things is different, of course. I'm a mechanical engineer by training so as a consequence I know some embedded languages like Assembly for certain chips, Tcl, as well as C/C++ and a little bit of Fortran. If you stay on the web side it's unlikely you'll encounter these very often. My Javascript kung-fu is weak because I pretty much never do web stuff.
It's all about having a relevant portfolio of demonstrable skills.
If you already know Java, C# should be a snap as they're very similar.
If you really want to do something different, start learning Clojure, ClojureScript, and React.
Don't look back years later to the answers in this question only to realize you had set a goal you wish you hadn't.