Typically the IRS can set you up with a payment plan that's a portion of your income. Its time to find a tax lawyer, not a CPA about this. Settlement/compromise, installment plan over a long term, and even bankruptcy are options.
If you are unable to legitimately pay (not working and unable to find work by being on unemployment) you will be able to qualify for the irs' settlement plan.
You are facing being broke either way, your basically going to have to figure out how long your going to be broke...
Also, a (relatively) healthy, single person with no children isn't going to qualify for many other programs.
Unemployment has also been severely cut, and the term severely shortened since the days of the 99ers. There's really not any government support other than unemployment available for able-bodied single people (they've even cut food stamps recently, which is one of the cruelest things you can do in a depressed economy.) Of course, if you become homeless the IRS will definitely leave you alone.