One tip I can give is that I ended up organizing each of my React components and mixins as a module in their own folders and files and my gulpfile adds the parent source path to the NODE_PATH environment variable. By adding the coffeeify transform and .coffee extension to the browserify gulp task I can just do this in my code:
SomeComponent = require 'react-components/some-component'
SomeMixin = require 'react-mixins/some-mixin'
No need to worry about relative paths or if it is CoffeeScript code or plain Javascript.The other tip is to NOT require react within your browserfied code. Just load it as a script tag before your browserfied code and use window.React to get a reference.