We have two people who handle all our infrastructure. We still needed two people available to handle all our Azure infrastructure even though they'd spend less time doing things (N+1 failover).

Also Microsoft doesn't give a shit if you're down past a status page and profuse apologising and perhaps a pro-rata refund if you complain like a bitch and wave a big "fuck you, AWS next time" at your licensing contact. That's not how to do business.

Our guys actually get up at 2AM and drive to the DC and fix shit if it goes wrong, which it inevitably does (less often than Azure I will say).

Downtime costs you more in reputation than you can gain from the cost savings of not having your whole world under your control.