Monsters will pick up items. If you are in the dwarves mines and there's a mining dwarf about, gnomes and other creatures will pick up the piles of rocks they leave behind.
Additionally monsters with the right flag set will often use items. This can reveal their blessed/uncursed/cursed status ("The dagger welds itself to the goblin's hand!") or identify the item - which is sometimes a real pain, when a consumable you needed is used. ("The gnome zaps a wand of lightning! You die...")