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Last time I tried, no. This is going from memory so I may be incorrect, but the WP emulator required some level of hardware virtualisation that VirtualBox (at least) could not offer in that nested way.

Parallels supports this nested virtualization. The WP 8.1 emulator requires HyperV which Parallels supports. I've managed to get this working on a Mac with a Parallels VM running Windows 8.1 running a Windows Phone 8.1 VM. It... worked, but needed lots of memory.

You can get a free VM from MS to test under IE at https://modern.ie/en-us/virtualization-tools

On the mac, they are support VMWare, VirtualBox and Parallells.