I'm skeptical about nootropics. The "nootropics of yesterday" weren't good, and I think the same will be shown of today's. Exercise and good diet are better, and there is no danger.
What I see is where the last generation of drugs had the shotgun approach and a lot of side effects, the newer drugs are more targeted, effecting more specific areas of the brain exclusively, and are also a lot more potent.
In my recent experiments PRL-8-53 and estradiol stood out as making changes to my thinking that were well outside the capability of even the best diet and a rigorous exercise routine, and I have tried that approach.