I'm certainly interested in trying it out! I've really only gotten hands on with virtualizing Linux within itself. Being more advanced than the average user I've never had much of a desire for running Windows apps within Linux (just switch partitions), and I definitely try to roll with option 1 for personal purposes. I love trying out all the different kinds of OSes. I'll take a look at Qubes though; even though I'm not dependent on Windows, investigating ways to help others break their dependence is highly beneficial for everybody including myself.