Depends on implementation.
NFC has that "secure element" thingy, that is, a TPM, like a SIM card. Implementations may vary. I'm unaware on actual Google Wallet NFC implementation, but I heard rumors (which are not certain by any means) at least Samsung had some hardware-assisted keystore. And I doubt Visa or MasterCard would permit Android vendors to do things on a phone's base OS a manner that could be exploited with a software hack.