It doesn't matter if it's otherwise natural. Nature is inconsistent in dosages (so diverse perspectives can flourish) and doesn't have ulterior motives.
Maybe it brings down suicide rates, but what other effects does it have? Does it affect the likelihood of voting for a political party or cause? Does it affect the likelihood of political participation in general?
It's kind of like CO2 levels in the atmosphere. Higher levels will have some effect; we're basically arguing over the significance of it, what to do about it (if anything), and whether politicians can be trusted with the power to make those changes.
Similarly, mind-altering substances will affect aggregate political behavior. Once someone finds out how, they will use it to their advantage.