India's ability to Manage Significant space exploration programmes on a Shoe string budget is driven in part by the need to innovate on a "ShoeString" budget. What we as a race desperately need is low cost access to Space - which perhaps may not become such a priority if NASA is allowed to influence ISRO.
On the other hand maybe ISRO will influence NASA & wewill get the best of both - super low cost missions with super advanced payloads :)