For those willing to set up DNSCrypt, I strongly recommend it. DNSCrypt.eu is my current favourite provider (OpenDNS has been pretty worthless) and is available over ipv6 too!
I for one has been pretty happy as a home user with OpenDNS: dead simple DNS filters to make sure kids don't surf on youporn and youreligion
Especially when 8.8.8.8 works so smoothly, with a backup on my ISP's service.
http://www.opendns.com/no-more-ads/
I used GRC's DNS benchmark tool to discover this. Also the particular OpenDNS servers which responded faster were different from the two that they tell you to use, so the fast response is probably helped by low load (fewer people using these undocumented servers). Going from memory because I'm at work, I think they ended in 202.222 and 222.202 and 202.123, whereas the officially listed ones end in 222.222 and 220.220.