Chrome is the only app I have on my Macbook Air that pushes it into overheating, turning it into a lap-frying iron skillet.
This is even more obvious on older Macs. I've got a Core 2 Duo mini that absolutely chokes on more than a few tabs in Chrome/Chromium, but runs acceptably well with Firefox even with ten or more tabs open, and flies with Safari. I really wish someone would put out a Chromium based, stripped down browser for OS X versions older than Mavericks. I think the rendering engine is solid, it's all the fluff that slows it down.
Which brings me to another point: cross browser testing is important.
But we're working on improving that, too :)
(yeah, Firefox dev here)
(then hiding user lock-in as innovative, minimal UI)
Chrome also does better at hardcore number crunching, somewhere on the web, there's a demo webapp that tries to recreate images using procedural and genetic algorithms. I tried to find it, but I couldn't find it. Performance on Chrome however, is a lot better than on Firefox.