It's complicated.
On one hand, traditional regulation keeps small or part-time players out of the market, because regulatory overhead is too high. The relative burden of regulation on large companies is much less, because they can amortize the cost across more business.
On the other hand, this only works if these smaller players get relief from regulations -- which means that they are operating outside the laws and regulations. For instance, turning an apartment building into a hotel via Airbnb sidesteps rules around zoning, tax collection, housing policy, etc. You could decide that these regulations are just annoying red tape, but they were put in place for legitimate purposes in the past and it seems like we ought to at least consider the impact before we throw the baby out with the bath water.
A third argument is that peer to peer marketplaces are changing the balance of power between producer and consumer. As a consumer, this sounds great -- but the person at the other end of the line is now an individual, not a giant corporation. When I have a bad cab ride, I go on Facebook and bitch about it, and life goes on. When I have a bad Uber ride, I give the driver one star and they may very well get fired -- and Uber will just replace them with one of the teeming masses hoping to make it rich driving strangers around for a living.