The first Python web framework I used was Django. I'm really glad I came across it first because I was inexperienced at the time and it forced me to adopt a lot of good practices.

However, now that I'm more experienced, I can relate a little to what Aaron is saying here. Learning all of this boilerplate stuff is annoying! Recently, I started contributing to a friend's rails app and I found the process of learning how to use each separate little tool tiresome.

This is why I like Pyramid - it starts off dirt simple. Hello World is almost as short in Pyramid as it is in Flask. As you grow, you can start organizing and adding different things as you need them. It has absolutely 0 magic. I find Pyramid to be a happy medium between Flask's minimalism and Django's extensibility.