Seriously, I know this won't appeal to everyone, but there is a solution to worrying about key combos causing RSI. Just don't touch type. Do embarrassing hunt-and-peck typing. I'm a professional programmer and long-time emacs user and I can't touch type for shit and it doesn't affect my career and my hands and wrists have been completely free of any trouble whatsoever (to current age of 36). If hunt-and-peck leaves you typing slower than you can design software solutions in your head then find a more challenging job.