I am very comfortable with make, my coworkers however are not. Every preprocessor comes with a command line interface, easily accessible and understood.
The only useful feature of these build tools is hot reloading. `npm gaze` even provides a somewhat working fs.watch interface which works good across platforms.
I am not sure if that justifies 70mb of additional dependencies and the "we can solve that with a grunt plugin" mentality devs get. Our Gruntfile is 440 lines long :/