I love the iTerm2 + tmux + vim + zsh environment. It takes a little time to figure out how to juggle the configuration for them, but once you do, it's super efficient.
Are you dotfiles openly available? I have the same set of tools, but still find things are slightly off... would love to compare notes.
I'm using the same setup (plus spf13.vim, powerline and Oh My Zsh). It looks beautiful and works very well. Here is a screenshot of my setup: http://postimg.org/image/9jqokq0ll/full/