Obviously it's personal, but the main issue I've always had with Alt-Tab is that as soon as you have more than 2 windows, getting to a specific application is now something you have to think about (or hit key, look, possibly hit key again). Since I'm often doing web development, I usually have a terminal open, an editor, and a web browser. Except for terminals, I pretty much always have everything full screen - the benefit is that Super-1 gets me to terminal(s), Super-2 gets me to my editor, and Super-3 gets me to the browser.