"Mac OS X interface and ergonomy is (as said by apple) not 'compatible' with the focus-follow mouse mode. Why ? Because a single application interface is split into lots of different elements. For exemple, you use an application like photoshop or word, you'll have different panels floating around the main window. With sloppy focus mode enabled, with an application below, you would'nt be able to reach them. And how should they consider the desktop, which is, finally, just a 'root' window managed by the Finder..."[1]
Here are some more.
"Sadly, it seems that for the time being there is no good way to do this in OS X."[2]
"The fundamental problem with sloppy focus on the Mac is that the menu bar is always associated with the currently focused application; if you had sloppy focus, accessing the menu bar for a specific application would be supremely difficult."[2]
[1] - http://jeremy.zawodny.com/blog/archives/000149.html#comment-...
[2] - http://superuser.com/questions/27306/focus-follows-mouse-or-...