I'm American and have lived overseas for several years and the currency exchange rates in combination with the 10-20 USD fees are a constant annoyance. And an annoyance for my startup which operates in USD but does business in several countries. It badly affects margin for smaller payments.
I'm a big Amazon Prime customer and I do a lot of purchase for family and friends for delivery in the US. I don't dare use my overseas credit card to pay for it, but if Amazon were to accept BTC I could pay from where I live. That would be very valuable to me personally.
I'm interested in bitcoin because it takes control away from traditional choke point exchange bank and also could serve as a 'world currency' of sorts. I also think that it would make possible a lot of cross-border sales that currently face real practical impediments.