I recently had a problem where I had to render tables that could have around 750 columns and 40 rows. I tried it with angular and it would cause everything to stop for around 90 seconds (that was the initial version with some poorly written directives inside of it, afterwards I tried making another angular one and it still took around 10~ seconds if I recall correctly).

I rewrote it in React and got the render time down to around 600ms~ Not GREAT, but far more acceptable than a couple seconds. It's worth noting that the react version doesn't do anything fancy, it just has to display the table with some tooltips. (There's a lot of room for improvement, for example, I could only render whatever amount of rows are in view and defer rendering the rest.)

I tried Griddle and, if I'm remembering properly, it took around five seconds to render a 750x40 table. The overhead of all the features they provide made it a suboptimal solution for us :(.

Unfortunately, I don't think you can optimize horizontal scrolling as easily as you can optimize vertical scrolling. I looked around as well and was unable to find a suitable library.