Human biology is an extreme hurdle on our way to achieve the unachievable: having to sleep, eat, excrete etc. Are there any tech and drugs being developed to deal with these things? For now I'd be contempt to at least control my sexuality :D
As usual, be careful, I'd say have sugar around.
As for the last point you mentioned there are drugs for this, I just have a feeling you'd rather try without but I'm no expert.