If anything it feels like io.js might make it out alive if Node turns into something akin to jQuery.
It isn't clear that node had to go that direction, or even that they can't change course now.
jQuery 2.x dropped support for <= IE8.
While all the new stuff has value, to me the value of frameworks will always lie in prototypes and small projects, with big production projects needing the flexibility of libraries.
I don't think jQuery will be going anywhere until the DOM itself evolves past a need for it or we evolve past a need for the DOM