* Friction of movement was higher and "stickier" regardless of surface. * Grip was less comfortable because I had to push my fingers against the top edge. * Cursor motion was noticeably lagged and jerky. Admittedly this is going from a corded gaming mouse to a bluetooth mouse, but I don't care. I didn't want cordless anyway.
My only problem with the DeathAdder is that the Mac drivers are horrifically bad and the third party alternatives (SteerMouse etc) aren't much better. I've found that I can configure some settings on a Windows box which configure firmware in the mouse itself (mostly DPI modes and disabling the lights). Get these settings right and it works pretty well plugged into a Mac with no third party mouse software.
You can actually recover from this with a full power down and restart, OS X tries to detect this condition and turn Bluetooth back on. But sometimes it doesn't work and requires a PRAM reset.