We know that technology, along with research, have proven very beneficial for devising better drugs, better ways to consume drugs, and better ways to produce drugs.
We know that already the concept of rolling up dead flowers to smoke has been superseded by vaporizers delivering 5 - 10 times more potency without all the smoke.
We know that weed has been excluded from even basic studies, leaving much to be explored and much to learn. Alongside the studies that have not been done lies innovations and technological and scientific enhancements that have not been invented yet.
There is no reason to assume we can only ever consume very tiny volumes of weed with fire, like our ancestors 700 generations ago.
Physiologically, you would lose motor function long before you were able to kill yourself. So maybe in 2056 if somebody produces a machine that lets you take in 50kg of THC in a single hit, don't use it.
[1]: http://druglibrary.org/schaffer/library/mj_overdose.htm