> But that’s just the tip of the iceberg. As Boyle and Hill point out, the men who were circumcised got additional counseling about safe sex practices compared to the control group, and then they had to refrain from having sex altogether for the simple reason that their lacerated penises had to be wrapped in bandages until their wounds healed — leading to what Boyle and Hill refer to as “time-out discrepancy” in the quote above. By contrast, the non-circumcised men got to keep having sex during the full two month period during which the treatment group was in recovery mode. Then (due to a statistically significant effect having been detected) the trials were stopped early — which tends to lead to an overestimation the true effect size of the treatment.

http://blog.practicalethics.ox.ac.uk/2012/05/when-bad-scienc...