Change your line of business (I went in to alternative energy for 5 years)
Learn a new trade (for me: metal working, Cad-Cam)
Right now I'm again going through such a phase of change, I have absolutely no idea what it is leading to but so far it has been extremely interesting.
Life is all about the journey.
Security in life is worth absolutely nothing, as soon as you feel that you are becoming 'secure' that's an excellent opportunity to kill that before it becomes a habit.
The flip side of that is of course that the freedom to do as you please (within the limits of the socially acceptable) is just as addictive or even more so.