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I'm curious, is there any real-world application for this? Or is it mostly interesting from a research perspective?

It seems like this wouldn't perform very well in the real world for most applications, but I could see it being useful for very simple architectures.

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My final year project was a hardware implementation of this. My group made an 8 core coprocessor and an OpenCL-like implementation complete with an LLVM IR to SUBLEQ translator. We actually got performance better than the proprietary NIOS II e soft processor on our image processing demo (Y colorspace conversion).

Well it could be interesting as a test architecture for a new logic family as long as you have wide memory.

The Manchester Baby was the first programmable electronic computer and was close to a single instruction computer. It can emulate the single instruction computer with 5 of its 7 instructions: load, subtract, store, skip if negative and jump. The two extra instructions were halt and relative jump.

http://en.wikipedia.org/wiki/Manchester_Small-Scale_Experime...

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