Ask HN: What's your go to for all things antivirus on OS X?

I put in ESET at a previous organisation I worked at and was actually amazed at how easy and straightforward it was to install and manage (simultaneously on Macs and PCs).

http://www.eset.co.uk/Home

The solution we had in previously to this was McAfee and it was a nightmare to update.

I use Sophos (free) and I also use Little Snitch as a firewall.