Macbook off to the side for skype, videoconferencing; use it for development when on train or at library.
But main system is 8 gig dual core ubuntu with 20" monitor, and second desktop with 20" monitor. Main desktop (athalon 64) has nice zip to it.
As someone else said, the main thing is the keyboard. I have the kenesis to reduce serious fatigue. I can't type long on anything else.