From the linked page:

  Why ? There are already mod_wsgi, flup and lot of protocols (fastcgi, scgi...). 
  Is this faster or simpler to configure ?

  Stop acting as a Rails user ! Deploy of python web applications is not a problem.

  No need of ultra-hypeous next-fu*king-useless almost-working deploy technology.

  The challenge in the python-world is now "features", uWSGI is a feature rich
  application, developer (and administrator/security paranoid/business environments) 
  friendly. Stop.

  Other deploy systems, works very well, this one does only more things.