Oh yeah, it's not a problem or conflict. Many of the examples people give tend to remap similar or the same keys for splitting in vim and tmux or navigating between splits (alt or ctrl + hjkl for navigating them).

I'm looking for more of a mental model or workflow of when to use vimsplits over tmux splits and how to navigate. I generally avoid vimsplits because I haven't found a good workflow to use both and my muscle memory gets messed up when I mix them.