I've been using Fedora pretty solidly since 20. I use it in a VM to get all of my "actual work" done and just use my host machine for email and web browsing. It's been pretty stable for me.

The main reason I use it is that our production environments run CentOS and I want to get used to upcoming features before they're included in mainline (systemd, firewalld, dnf, python3, iproute2, etc).

Fedora has actually gotten a lot better since around Fedora 19. If you haven't given it a shot in a while you might be pleasantly surprised.