If you're looking for realism in your apocalyptic nightmare scenarios, there's an ooooold DOS game called Bravo Romeo Delta you should track down. I wrote a little bit about it here: http://jasonlefkowitz.net/2014/11/choreographing-armageddon-...
It's fallen into abandonware hell, so you can't buy a copy at GOG or anything like that, but cough I'm sure you could find a copy if you looked on the right sites.