How fast can we sequence now? What are the error rates?
Error rates are in the region of 1 to 0.1% generally.
I've never really worked directly with capillary data but understand it's error rate in early bases is limited by the amplification step. Which would be ~0.0001% (1 in 10000).
That said there might be a coarse filter (based on signal intensity etc) that would identify a subpopulation of high-throughput reads which have a <0.1% error rate. But I don't believe I've seen that reported. I'd be interested in hearing from anyone who has thoughts on that though.