I was reading a summary of Macbeth with my kids this morning and came across several "lost in translations" from English to English - mainly through changes in pronunciation and meaning of words changing over time. For example, the words "fear" and "fair" would have almost sounded identical in early 1600 leading to a play on words of the two themes in Macbeth.
I also came across this interesting article on Kurosawa's interpretation of Macbeth, http://www.academia.edu/3306558/Lost_in_Translation_Reconsid...
I suspect there is a lot lost in translation, which can be challenging when reading old texts.