some background: the ClojureScript compiler has recently been bootstrapped, effectively giving us two different versions of the compiler, "ClojureScript JS" which only relies on a JS runtime, and the original "ClojureScript JVM" which will continue to be the default choice, partly because the benefits afforded by the Google Closure compiler (written in Java) are huge and irreplaceable.
The "ClojureScript JS" compiler cannot replace the original compiler fully, but is already finding some great use-cases, such as this new insanely fast Planck REPL, targeting new platforms like iOS (see Replete, Ambly, React Native), an in-browser try-it-out REPL for our upcoming website, the ability to try out new libraries from a webpage, and possibly adding ClojureScript support to CodePen.
Lot of great stuff coming.