In fact, winning can make it worse. When you're successful and depressed, the dissonance between your outward success and your inner self loathing/misery can be very painful. You think, all these great things are happening and I still can't be happy. I must really be a worthless, ungrateful piece of shit if I attain everything I ever dreamed of and that's still not enough for me. If this doesn't make me happy, that means I'll never be happy. bla bla bla depression talk.

Not that this is guaranteed, but I've experienced it and I would imagine others have too.

Yes, depression is usually not about the money, but personal issues. My hardest days personally have been when things were going well and best were when I was unable to keep the lights on/pay bills. When the business was almost failing I had my significant other with me 24/7. After I ruined the most important relationship in my life, the business improved dramatically and I was mentally in a far worse place.

I would happily leave the company to get her back or undo losing her. That's what people don't understand, you're an entrepreneur for the journey not the money (even if only subconsciously). Thus, people shouldn't assume there are money/ startup problems when someone is depressed.

I feel terrible for her family as well, perhaps not even knowing exactly what led her to do this (in which case some people may end up feeling guilty).