Although I'm very hesitant to put too much faith into anything in the area of nutrition and health based on a single study, I do recall reading a longitudinal study a few months ago where they looked as various carb/fat/protein ratios in diets and basically found that both high carb/low fat/high protein and low carb/hight fat/high protein diets promoted weight loss and increased overall health, and that high carb/high fat/low protein diets tended to cause a lot of health problems and participants either gained weight or lost weight at a much lower than expected rate based on their calorie deficit.
Anecdotally, as a person who has struggled to control my weight (420lbs -> 100lbs -> 200lbs -> current back down to around 190lbs), I found that a low carb/high fat/high protein diet did help me lose weight and my vitals (based on blood pressure, resting heart rate, and CBC with metabolic panel) were extremely good during that time (although I suffered from bradycardia and low blood pressure for a time), but the high caloric density of fat made it very difficult to feel satisfied with the amount of food I was eating to maintain a consistent calorie deficit. I'm losing weight a little more slowly on a high carb/low fat/high protein diet, but my vitals are still good (bp and heart rate are more normal than the high fat diet, but I'm struggling with anemia now) and it seems more sustainable for me in the long run.