You're right, some people can pull it off and successfully. It's great for those who want to and can. I think my implicit point is not everyone _should_ want to. Career is not an end goal. Career affords us a path to a life we desire. Some people actually enjoy and want a real livable work-life balance --not just the HR PR diluted version.

However, yes, it's great that some people are single minded and discover new drugs and treatments for disease and contribute to accelerated human progress.