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Alex3917

30,632 karma · joined February 23, 2007

Co-founder @ FWD:Everyone (www.fwdeveryone.com)

https://alexkrupp.typepad.com

https://twitter.com/alexkrupp

alex.krupp@gmail.com

[ my public key: https://keybase.io/alex3917; my proof: https://keybase.io/alex3917/sigs/fCFh_z2Dnx_9agwhK41ieQePaxwifpCJ9zpwDbWrTD4 ]

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Alex3917··on Young people are flocking to astrology
Astrology is a subset of astronomy, since astronomy is the study of things in space. But the part of astronomy that deals with how things in space affect life on earth is astrology. It's literally the definition. You can't just attribute a bunch of random bad things to astrology and then change the definition to make it fit your preconceptions. Literally just type "astrology definition" into Google.
Alex3917··on Young people are flocking to astrology
> Maybe I'm reading it too literally, but I think the question is just badly formulated.

It's not. The definition of astrology is literally the study of how bodies in space affect life on earth.

And if you don't believe in astrology, how exactly do you explain tides?

Alex3917··on CoQ4 is a functional substitute for CoQ10 and can be targeted to mitochondria
This thread is super interesting:

https://news.ycombinator.com/item?id=31306337

Alex3917··on A Caltech Nobel laureate celebrates his 100th birthday, then gets back to work
Dick Garwin: https://www.nytimes.com/2001/04/24/science/who-built-the-h-b...

https://rlg.fas.org/2020.htm

Alex3917··on A Caltech Nobel laureate celebrates his 100th birthday, then gets back to work
Apropos of Oppenheimer coming out, the guy who invented the H-bomb currently works as a covid researcher. (Or at least an amateur one, not sure what he’s actually doing.)
Alex3917··on Simpson Fan Grows Tomacco (2003)
That's not entirely surprising. The whole point of grafting is to clone the plant you're taking scion wood from. Are there any examples where choice of rootstock can affect things like flavor? I've heard of rootstock affecting things like vigor, disease resistance, and cold hardiness, but never anything like taste or psychoactivity.
Alex3917··on ‘The best blueberry’: how a tiny North American fruit took over Australia (2022)
> Wild blueberries are smaller, with blue and much more flavourful insides.

If you remove all the excess water from farmed blueberries, the taste is about the same. You just need to aggressively sweat them.

This obviously doesn’t work if you want to eat them fresh, but there are better berries for eating fresh anyway.

Alex3917··on Ask HN: Why is it assumed to be harder to bootstrap a Reddit-type site today?
All of these. Jonah Peretti has a good explanation here:

https://medium.com/matter/buzzfeeds-jonah-peretti-goes-long-...

It's not impossible, but it is much much harder.

Alex3917··on FDA says aspartame is safe, disagreeing with WHO finding
> Aspartame could possibly hold the title as the most scrutinized chemical in history

You could almost say that it's the Lance Armstrong of food additives.

Alex3917··on At Japan’s first winery, the country’s oldest grape lives on
> Perhaps we just value it less here in North America.

The reason we have less stuff like this in the USA is due to geography. We are a mostly flat country, rather than being mountainous or separated onto different small islands. Because of this, products produced via economies of scale can outcompete higher-quality artisanal products.

Alex3917··on Don't Take VC Funding – It Will Destroy Your Company
IIRC each time you raise a round, your chances of success go down by ~10x. Can't find a good cite offhand though.
Alex3917··on Don't Take VC Funding – It Will Destroy Your Company
> But in terms of total # of employees, total $ of turnover and profits I would expect it to be the reverse.

In general, the less money that startups raise, the better their returns:

https://techcrunch.com/2016/10/15/overdosing-on-vc-lessons-f...

There are a number of reasons for this, a big one being that marginal revenue is always the least profitable:

https://techcrunch.com/2017/10/26/toxic-vc-and-the-marginal-...

Alex3917··on Don't Take VC Funding – It Will Destroy Your Company
> But no less unusual than building a successful company to begin with.

Statistically, companies that raise venture capital are vastly less likely to succeed than those that are bootstrapped.

Think about it this way: from the perspective of VCs, the most successful apps of the iOS era were Uber and AirBnB. But from the perspective of entrepreneurs, the most successful app of the iOS era was the Flashlight app.

Which one do you think was easier to build?

Alex3917··on Two corpse flowers are blooming in the U.S.
Second hand knowledge. I have a friend who worked at one of the biggest botanical gardens in the United States.
Alex3917··on Two corpse flowers are blooming in the U.S.
Most botanical gardens have a dozen or so, but they only bring out one that’s blooming when they think it’s a good year to fundraise. While it may be true that any given one only blooms every 20 years or whatever, in practice they’ll bring one out when the stock market is at its peak, or at a big anniversary year or whatever.
Alex3917··on Tea as Hepatoprotective Agent: A Revisit
Interesting, considering how many people get liver damage from taking green tea extract and EGCg.
Alex3917··on Bret Victor update
> This is the talk that made him famous.

He was already pretty famous before that from Magic Ink, if not even earlier work.

Alex3917··on The Cluetrain Manifesto (1999)
Rule #1 is "Markets are conversations."
Alex3917··on The Cluetrain Manifesto (1999)
> "Cluetrain" though seems far more like mush to me.

The fact that you don’t see the irony of posting this comment on a web forum sponsored by a startup accelerator shows that it’s probably by far the most influential of the three.

Alex3917··on US Congress doubles down on claims of illegal UFO retrieval programs
You learn to speak Chinese.
Alex3917··on US Congress doubles down on claims of illegal UFO retrieval programs
> This is a push from Congress to force programs into the open that are secretly capturing Russian/Chinese UAVs right?

No. The USA has spent the last several decades putting most of its military budget into aircraft carriers, which will all be sunk within the first 24 hours of any conflict with China. This is just a last ditch effort to try to trick China into thinking we might have some kind of deterrent.

Alex3917··on US approves chicken made from cultivated cells
> farmers spend a lot of effort growing things that aren't salable, or are barely so, like bones and feathers

These are the main ingredients in Plant-tone. This product might not be as relevant to folks who live in cities or in rural areas, but folks who live in the suburbs go through it like crazy.

Alex3917··on Daniel Ellsberg has died
This. They were literally torturing Chelsea Manning at the time.
Alex3917··on Metformin shown to prevent long Covid
Is there a good explanation of the mechanism of action? Metformin is also a Mitochondrial Complex 1 inhibitor, so I would be curious about Annonaceous acetogenins.
Alex3917··on Launch HN: Resend (YC W23) – Email API for developers using React
> There isn’t much innovation happening since email is stable

There are probably more Show HN launches involving email than any other product category.

Alex3917··on First impressions: Yes, Apple Vision Pro works and yes, it’s good
> I don't understand why there is no AR or VR killer app for this thing.

Because if you go outside wearing this you're going to get instantly mugged. If they were to release something like Pokemon Go before the price comes down, that would likely just result in a bunch of kids getting murdered on the subway or whatever. Much better to drive down the costs by first selling it to people who are excited to use it for coding or whatever.

Alex3917··on Doug Rushkoff on why tech billionaires are in escape mode
Given that the article couldn't even get his name correct, how accurately do you think they're going to be representing his ideas?
Alex3917··on OpenAI CEO raises $115M for crypto company that scans people’s eyeballs
There are only 8 billion people on earth, so even if every single account were fake that's still a huge improvement over the status quo where someone can spin up 8 billion fake accounts in an hour.
Alex3917··on Dandelion Root Recipes
Most lawn weeds were brought here as food. One obvious exception is buttercups, which are poisonous.
Alex3917··on Supreme Court rules Andy Warhol’s Prince art is copyright infringement
Given the fact that the Warhol Foundation has been accused of not authenticating legitimate pieces owned by the "wrong kind" of people in order to drive up the perceived value of the collection, it's still kind of poetic justice.
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