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ColanR

3,951 karma · joined October 23, 2016

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ColanR··on Vitamin D deficiency and Covid-19 mortality [pdf]
Thanks for the response. I'm curious what your wife thinks about this article [0], mentioned elsewhere in this discussion. It makes the case that the current RDA for Vitamin D is based on a statistical error, and that the recommended dose should be closer to 8000 IU for young adults.

[0] https://pubmed.ncbi.nlm.nih.gov/28768407/

ColanR··on Vitamin D deficiency and Covid-19 mortality [pdf]
There's other studies cited in this discussion. Those are peer-reviewed and do back up what the post is claiming.
ColanR··on Vitamin D deficiency and Covid-19 mortality [pdf]
I'd tend to agree with you. There's a lot of pharmaceutical money to be made on this crisis, especially if Covid-19 becomes seasonal. Don't want to waste that opportunity by treating it with something cheap like Vitamin D.

In line with how Monsanto covered up studies showing the dangers of Roundup (and faked other studies that indicated no danger, and did a fair bit of astroturfing, iirc), I'd expect to see a lot of misinformation in the future about the ineffectiveness - maybe even the danger? - of Vitamin D supplements.

ColanR··on Vitamin D deficiency and Covid-19 mortality [pdf]
Right now, I'd rather have a calcium problem than a Covid-19 problem. Also, some of the studies being thrown around in this discussion have mentioned that safe levels of Vitamin D are much higher than a lot of medical professionals actually think.

> there is virtually no risk of toxicity in supplementing up to 10,000 IU of vitamin D3 daily

https://sci-hub.se/https://www.sciencedirect.com/science/art...

ColanR··on Vitamin D deficiency and Covid-19 mortality [pdf]
> too much confidence in published research and not enough confidence in your local health officials

I can't figure out if you're being sarcastic, or if you really do think that a local politician knows more about medicine than is contained in actual medical research.

ColanR··on Vitamin D deficiency and Covid-19 mortality [pdf]
Looks like this has been posted a lot on HN recently [0]. Previous Vitamin D & Covid-19 discussions that garnered some comments:

https://news.ycombinator.com/item?id=23023703

https://news.ycombinator.com/item?id=22463713

https://news.ycombinator.com/item?id=23119949

https://news.ycombinator.com/item?id=23390264

https://news.ycombinator.com/item?id=23349962

https://news.ycombinator.com/item?id=23167802

https://news.ycombinator.com/item?id=23188675

https://news.ycombinator.com/item?id=23083619

https://news.ycombinator.com/item?id=22600685

[0] https://hn.algolia.com/?dateRange=pastYear&page=0&prefix=tru...

ColanR··on Vitamin D deficiency and Covid-19 mortality [pdf]
> Although this is a notable finding it's important to remember that it doesn't lead to the conclusion that supplementing vitamin D will be very beneficial here....we don't have a ton of good science to back up if curing a vitamin D deficiency via supplementation of pure vitamin D is really nearly the same as getting it naturally

I don't know what you mean by 'a ton', but there is good evidence that Vitamin D supplements do provide much of the same benefit [0] [1].

> Ultraviolet radiation (either from artificial sources or from sunlight) reduces the incidence of viral respiratory infections, as does cod liver oil (which contains vitamin D).

[0] https://pubmed.ncbi.nlm.nih.gov/16959053/

[1] https://sci-hub.se/https://www.sciencedirect.com/science/art...

ColanR··on SpaceX test flight of Starship SN-5 [video]
That's what I was thinking. At the very least, they'll either have to come up with some very fancy welding rod matrials, or train their welders in some interesting techniques. Reminds me of the difficulties in welding aluminum.
ColanR··on Math Overflow users resolve PhD thesis crisis
> What's the minimum I need to do to get out of here? Not, "What amazing interesting thing could I explore?"

I totally get it, but it makes me sad. That line, right there, probably explains why it's so few people who actually get to make the big discoveries.

ColanR··on Show HN: Visualize Graph Theory
Changed a few colors, and added a background that makes the page lag. Didn't change the text or even the order of the levels. The small size of the bounding box is because he didn't expand it from the original.
ColanR··on Stingrays and Dirtboxes: how cops can secretly track your phone
That makes more sense, since a similar comment that replied to it was also marked [dead]. Thanks for the clarification.
ColanR··on MNT Reform open source laptop with trackball
I use the knockoff chinese batteries for my thinkpads that cost ~ $30. Haven't had a problem.

But that's not what I was talking about. I was referring to the GP comment, about using individual LiOn 18650 batteries that can be individually replaced. Those cost a few bucks each, and your X220 battery has about 6 of them inside. That's what the MNT Reform does, as well, which is what's so cool about their batteries.

ColanR··on The land with no face masks
Not the best source, but seemed interesting and worth a discussion.
ColanR··on MNT Reform open source laptop with trackball
I checked the US version of that site just now - those batteries are really expensive compared to the cells inside.
ColanR··on Stingrays and Dirtboxes: how cops can secretly track your phone
To whomever flagged the sibling comment by throwaway_drt2: they were not being crude, they were referring to the cell site simulator called the Dirtbox. [1] Don't be so trigger-happy.

[1] https://en.wikipedia.org/wiki/Dirtbox_%28cell_phone%29

ColanR··on Why aren’t we talking more about airborne transmission?
Don't you love it when people force their opinons on you, 'for your own good'?
ColanR··on Why aren’t we talking more about airborne transmission?
> might solve the recirculation issues, no?

No.

Another half-baked 'solution' will cut the infection rate by some fraction of a percent, and we'll be right back where we were before: right here, asking why we aren't being told about proper solutions.

Just like the masks, which as TFA is discussing, don't actually address one of the primary transmission vectors.

ColanR··on Why aren’t we talking more about airborne transmission?
Yeah, I noticed and fixed the search.
ColanR··on Why aren’t we talking more about airborne transmission?
To the other folks replying: I looked up the protests on ddg images, and about half of the protesters in those photos were wearing masks.

https://duckduckgo.com/?q=blm+protest+2020&iar=images&iax=im...

ColanR··on Why aren’t we talking more about airborne transmission?
> Making sure everyone wears masks will, at the scale of the general population, reduce the infection rate by some noticable percent.

I said that.

ColanR··on Why aren’t we talking more about airborne transmission?
I have several (medical) doctors in my family. They were pretty clear from the beginning that what the WHO was saying was BS. They pretty much agreed with what you're relating; I don't think it's doctors in general who are ignorant of how a virus gets transmitted.

I completely agree with your first point; but what we need to seriously question is the cherry-picking of sources that were paraded in front of us by the media.

ColanR··on Why aren’t we talking more about airborne transmission?
We probably aren't hearing about it because it's something we have less ability to protect against.

I remember a popular comment here a while back mentioning that epidemeologists' job is partly public relations, trying to figure out what they can tell the general public that will minimize the viral spread.

Making sure everyone wears masks will, at the scale of the general population, reduce the infection rate by some noticable percent. It's also something everyone can do, and it gives everyone a sense of control over the situation - enough of a sense, at least, to prevent chaos.

Talking about airborne transmission, though? The kind of masks that can protect against that are hard to come by. Not to mention that the virus could enter via the fluid of the eyes (not trying to add conspiracy here, just trying to make a point about the difficult reality of preventing infection [0]). Bio-rated goggles and N95+ rated masks are more than we can expect from a public that's making face masks out of bandannas.

I think we're seeing very pragmatic statements being made, that are tailored to a public that can't enter full biohazard mode and need to not panic.

[0] https://www.biorxiv.org/content/10.1101/2020.05.09.085613v2

ColanR··on Ask HN: Geopolitical forums similar to HN?
I love reading that site.
ColanR··on IBM Fully Homomorphic Encryption Toolkit for Linux
I don't have a great understanding of the algorithms here, but I have a question.

If I had some data encrypted with these tools, which I made public for multiple entities to process, is it possible for me to allow them to add data to the encrypted system? i.e., is there a way for multiple entities to add more data to the encrypted data (and do calculations with the encrypted contents) while only one party is able to extract the results of the whole resulting collection of data?

ColanR··on Tampa teen accused of being ‘mastermind’ behind Twitter hack
> It should not be this complicated to respect laws that just enforce minimal good practices.

It's not necessarily the compliance that's the issue, it can also be figuring out how to comply. IANAL, and I can't guarantee to myself that I can implement a site with policies that comply correctly. Better to just geoblock, because it's not necessarily worth the lawyer fees.

ColanR··on FCC approves Amazon’s internet-from-space constellation of 3,236 satellites
For everyone worried about these satellite's effect on astronomy, don't the new satellite launch capabilities that make "internet-from-space" suddenly feasible mean that telescopes could be more easily put in orbit too?

It seems like that would solve the light pollution problem. I have no relevant background, though.

ColanR··on Apple does not keep the 30% commission on a refund
Any recommendations?
ColanR··on Americans are getting more nervous about what they say in public
I'm really sorry, I linked the wrong article. The quote in my comment is from the abstract of this [1] study. It's a meta-analysis by a professor of epidemiology at Yale. He also wrote an op-ed that ran in Newsweek. [2]

[1] https://academic.oup.com/aje/article/doi/10.1093/aje/kwaa093...

[2] https://www.newsweek.com/key-defeating-covid-19-already-exis...

ColanR··on Americans are getting more nervous about what they say in public
You're deriving way too much from an uninformative article. "Given the drugs by her parents" doesn't mean they were prescribed by her parents. Did the article say whether there was no doctor involved?

Also. The girl had an autoimmune disorder, for which the same drugs are commonly used. Did the article happen to say whether or not she was already on the drugs?

The article also says nothing about whether the drugs had anything to do with her demise. It sure does imply that, though.

This is a cherry picked article.

ColanR··on Americans are getting more nervous about what they say in public
The specific circumstances where the drugs are effective aren't being met. I didn't look up the details before.

https://academic.oup.com/aje/article/doi/10.1093/aje/kwaa093....

> Evidence about use of hydroxychloroquine alone, or of hydroxychloroquine+azithromycin in inpatients, is irrelevant concerning efficacy of the pair in early high-risk outpatient disease. Five studies, including two controlled clinical trials, have demonstrated significant major outpatient treatment efficacy.

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