DaveZale

Also, what about stock options and getting vested? Some companies can offer tasty carrots. It's not always about the stick.

Anyone who has ever started their own business knows how hard (and rewarding) it can be- but you're just creating your own job. Nothing wrong with that. It is one of the best experiences in full accountability, but it's a job.

Brave browser helps a lot. I can't use some browsers due to the ad clutter. Some can handle the ads, some can't.

You need to write a book on these topics. You've already got the outline. I'll be first in line for a signed first edition. Seriously. A lot of us old timers who grew up with simpler, more user friendly software that nearly any user could streamline with their own code (even if it was just stacking macros into a small file)- a lot of us miss what was lost. Keep up the good work.

I could add, based on a few decades of life as an adult, that almost all of the abortion I've known of was motivated by concerns of inconvenience, chief among that including the economics and time requirements of child raising. It's a very thorny issue that ironically provokes anti-abortion activists to killing others, though this is rare.

And then I can't resist thinking about Kierkegaard, who pointed out that our anxiety about our behavior with respect to Christian morality is what keeps churches from turning into dance halls (and since your essay deals with extrapolation, maybe brothels or equivalent?)

So if infanticide, whether in the womb, or after birth, is already mostly a convenience issue, there isn't much Christian morality there at all. But is it pagan? What kind of paganism? There is a huge menu to choose from among billions of non-Christians.

If my thinking, writing this, seems unclear or objectionable, fine. Yours is a well written, thought provoking essay that clearly draws upon thoughtfulness and life experiences. But maybe I am way too overanalytical and want to put "paganism" in a box with clear boundaries. Are there any?

yup it's true, and as some point out, consumption in the early morning, when we all get a proinflammatory, normal response, is perfect timing for the antioxidant flood of coffee to counteract it all.

The rest of the day is another story, every day! Hopefully one of the better stories.

My wife had a small spinal tumor a few years ago. Detecting it required MRI with a contrast agent. Prior to the MRI, she was misdiagnosed several times. The MRI saved her from a wheelchair or worse. It was to the point where she couldn't walk far at all. The clump of nerve tissue was pressuring the spinal nerve. More than you wanted to know. But the fact is, this is an extremely rare occurrence of unknown origin. I am very thankful that she was referred to a specialist who recognized the need for MRI, and to the insurance that paid some of the costs.

On the other hand, general whole body imaging technologies can reveal the wear and tear of simple aging, and when the results are interpreted by specialists, it's very easy to get caught in a doom loop. As in, "now I screwed up my spine, look at all of that degeneration" - and this can trigger sensations of pain where no pain was previously noticed. It's a fact that most whose imaging results indicate a potential very painful condition feel little or no pain. But, some can begin feeling pain when they think something's wrong. So this kind of scenario needs to be addressed. Which is why folks like Dr. Amen will say that sometimes, it's all in your head. And if you have a reason to think that you're in pain, your head can invent an excuse to make you feel it.

All of that said.... the cost needs to come down. Get some competition in there. Of course, as patents expire, this will be inevitable. But whole body imaging by MRI is a lot safer than scans involving high energy radiation.

There are organizations in the US like Homegrown National Park, Wild Ones, and dozens of native plant societies that encourage rewilding of urban and suburban areas with plant natives. This is a really important step, too, in saving what's left of wildlife. The commercial focus on non-native grasses and ornamentals is sometimes a disaster for wildlife. Once the ecosystem is out of balance, it's not just a disaster for wildlife, either. Once the predators are gone, it's easy to get infestations of rodents and their diseases, noxious insects out of control, etc. It's not easy to re-wild a place, but the natural beauty of native plants and healthy wildlife, although not without inconvenience, has long term benefits for human livability, and relatively low costs.

One of my hiking buddies is a recently retired cardiologist. He is totally open to the idea that reduced heart disease over the past few decades may just have likely been caused by better dental care as by statin therapies. His attitude is that you need huge clinical studies to get any good conclusive evidence one way another. Good to see this!

another holy grail is hugelkultur. Bury agricultural waste beneath a foot of soil. You will get an amazing mycelial network that swaps sugars from plant roots to the fungi, with the fungi supplying minerals to the plant. And sure, go ahead, use sensors to make it all cool and measurable. I've tried this technique in my backyard shale soil. It works, including retaining moisture, so much less irrigation is required.

Bless her heart. And mind.

Fun facts: Having a cat that hunts mice can result in toxoplasma infections in those who come into contact with their matter. Also, cat dander can drive many humans into an allegic fit.

okay, but look at all of the other functions sox9 has: https://en.wikipedia.org/wiki/SOX9 Maybe some promoter tailored to cross the BBB would work? Not sure- The original publication is paywalled.

look on the bright side. Fecal transplants are expensive but this way it's free. Sorry, that's not me talking, it's my ADHD ;-)

Low-carbohydrate diet and/or frequent small meals is the first treatment of this condition. The first important point is to add small meals at the middle of the morning and of the afternoon, when glycemia would start to decrease.

opensecrets.org (if you're in the US) to see whose money your elected get - but then we have darker influences too. Go to DC and take a long walk, much is visible

green potatoes have solanine, toxic! They turn green upon light exposure

Pink Floyd may have also said, it didn't cross the road, because it wanted to stay out of the road because it wanted to grow old. Almost verbatim from the Animals LP

In grad school, we we required to attend 20 seminars in a semester and submit one page summaries of the material presented. For the first few, I had to take a lot of notes, then use those to construct the full page. But somewhere around the 10th seminar, I found myself taking almost no notes, then writing it all while it was still fresh in my head. This may have been the best, most useful course in the 32 semester unit program, though it was only one point out of 32. Why? I became a good listener, and a concise writer. FWIW. Of course, these exercises may have been more valuable with presenting the summary orally to a small audience and answering questions received, and some programs do that too.

Of course in a more analytical or engineering environment, the problem solving is also critical.

Pugsley's tunnels! The Adams Family old black and white tv show...

Well, I am very familiar with the workings of local govt homeless enforcement. Within 10 miles of my home are homeless encampments along a river. These poor people often end up with dozens of citations and fines. The only way to escape that, in the absence of money, is jail time, or go somewhere else and repeat the experience of more citations elsewhere. It is a "doom loop" - at some point, they'll need permanent shelter and services. So we need a solution. What is your proposal?

CHS is very readable. He has free samples of his books on his website. Very logical arguments, good social criticism. But I wonder if AI model training can recognize and discard the AI slop that is cluttering the internet now. It can be maddening. A recent slop piece on a stock that I own was titled "[ticker] drops 90% ..." after using 5-year old data from the highest point of a bubble. How much more of this will we see from unsupervised AI slop publishing? Will automated trading algorithms processing news feeds be able to recognize irrelevance? Just one example...

actually, getting them in one location may be very economical for getting homeless medical, dental care, and addictions treatment, but sure, some guardrails and scrutiny are required. Of course, it shouldn't be a dumping ground, on one hand, and not a magnet for easy living, on the other. It's a tightrope for sure.

Currently, incarceration for criminal offenses probably saves many lives, ironically. Not just those of potential victims, but those of the offenders as well. I've seen some examples of that first hand. But this may be a better option, if it has sufficient funding, staffing, planning and oversight.

Yes! As long as we don't confuse "Standard of Living" with "Quality of Life " - all the money in the world won't help with the results of eating a bad diet, all too often. For example, what's up with the overeating that results in obesity, diabetes and heart disease (all of which correlate with later cognitive decline) - then we need to inject peptides for curbing appetite? Sure, huge industry, big profits, trillion dollar stock valuations - big Standard of Living! But it's kind of "bass ackwards" - simply improving dietary habits could save us all a boatload of money and prevent completely avoidable lifestyle diseases. Sorry if this is "doomer" stuff - but there's an easy way out, and it can be fun, and good for the wallet.

Many solutions will be implemented. A lot can be done locally in rural areas, the old fashioned way, by having local farms grow some for the local community, not just for the commodities markets, for example.

Waste can be minimized. This year I donated several huge boxes of backyard potatoes to local food banks, and I learned a little about their supply chain. They make weekly trips to Walmart to snag unappealing produce, which would otherwise be deposited in the dumpsters. Discontinued or overstocked items are included too.

But changes in shopping habits can make the dollar go further. The loaf of white French bread or baguette for $3 may be very tasty and be consumed in a single meal, but the $6 loaf with 21 grains that weighs 1-1/2 pound can last all week and provide all the daily fiber you need in just a few slices!

Let's face it, half the food in the American supermarket is junk calories in brightly colored packages, heavily advertised to children to hook them young. It's not easy to quit comfort foods. Who doesn't like an oily, crunchy, salty snack designed for addiction?

Maybe this will be an opportunity to critically examine our eating habits, cook more of our own food, maybe grow some in the backyard, or support local farmers by buying direct and cutting out the wasteful middlemen?

Brave. Doesn't work with sone video feeds and pop ups but so what?

the quantum world does not have much overlap with common sense, for sure.

Towards the end of the paper, "space and time need not be physical" but instead, "uniquely consistent constructs by which one can describe events" ... so does this mean that space and time simply make the math work?

A PhD bud of mine says jokingly, skip the math, particles can eat each other, swap energy and sometimes emit a LOTof energy. Space is not what we think, apparently time isn't either

gotcha. Keep it simple. Sure, I have curry powder. The goat cheese may prompt a trip to the farmer's market. Or I'll get some online. But fresh and local are usually best.

moves at the speed of light even at rest! Wow... this is enticing.

nice. That's one approach to making it palatable. I have some Indian spices in the kitchen. This will be fun to try on a chilly day.

It's really interesting that this study actually directly measured blood cartenoid levels. When I was writing my thesis, I encountered another study from Sweden that measured blood dietary antioxidant levels there. Guess what the source of major dietary antioxidants in the bloodstream of Swedes was found to be? Coffee! The assay used was TBARS.

Interestingly there is a company in Taiwan making a propietary blend of botanical extracts to prevent prostate issues in older men. It's listed on the stock market. Prostate cancer is a major inconvenience and worse, often fatal for many men. But the Indian approach to pureeing vegetables with some fat might be an equivalent approach, less expensive, and better flavored ;-)

It's worth noting that the 3D-printed cornea was originally developed all the way back in 2018, at Newcastle University in the UK. Precise Bio, for its part, says it developed its 3D printing system in collaboration with clinicians over the last decade. That gives us a sense of how long it takes to go from breakthrough to application.

in the US, it's all about medical "billing codes" so that doctors can be reimbursed for services. What is diagnosed as AD is often the result of vascular issues. Or even long term oxygen deprivation during the night due to sleep apnea. Like cancer, there may not be a single "silver bullet" - it's a situation more like Parkinson's, which Oliver Sacks described as a "constellation" of factors. Whole books on the topic - good ones by conscientious MDs - have been written. One example is, "What if it's not Alzheimers" - good reading if an elder relative is having issues.