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DiffEq

217 karma · joined October 31, 2014

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DiffEq··on Most Extensive Reengineering of an Organism’s Genetic Code Now Complete
I have odds that this will not work out the way they think it will.

“They can also be made entirely dependent on synthetic amino acids in their diets, to allay the fear that recoded bacteria could escape from a lab and wreak havoc in the wild.”

I say this becasue of this well known experiment:

https://en.wikipedia.org/wiki/E._coli_long-term_evolution_ex...

Whether you accept the E. Coli long term evolution experiment as proof of evolution or not, it clearly does show at least the capacity for E. coli to figure out how to eat different things.

DiffEq··on A Journal of the Plague Year: Daniel Defoe's Account of the Great Plague of 1665
Here is a recent book on the Plague following real people in 1348:

http://cobblestonepub.ie/events/book-launch-1348-a-medieval-...

DiffEq··on Ask HN: Do employers care how long it took you to finish a degree?
The only time employers (that are worth working for) actually care about your degree at all is if you are being hired as an engineer, a lawyer, or a doctor.
DiffEq··on Ask HN: When you feel stuck in life
I do not disagree with you at all; however college or school does not necessarily educate you; the education you speak of can be obtained elsewhere these days and much more cheaply. This also is relatively new to the world - the ability to obtain philosophy, art, and other liberal arts knowledge without going to a college or university...not to say there is no place for it in institutions of higher learning; but for the vast majority of people a great liberal arts education can be obtained without institutions of higher education but the education of a civil engineer - not so much.
DiffEq··on Ask HN: When you feel stuck in life
9 times out of 10...if you did not major in Engineering or Science, Law, or Medicine then you should not be going to college. It is a waste of money and most importantly time.
DiffEq··on The Black Death: The Greatest Catastrophe (2005)
There is a new book coming out about this focused on the Black Death in Ireland: http://irishhistorypodcast.ie/the-black-death/
DiffEq··on Advanced Economies Must Still Make Things
It is about balance, independence and longevity of the nation. A diverse economy is more able to resist economic challenges of ALL types. It is also able to resist sudden turns in foreign policy (war) and maintains options for such a country if they find themselves at war with the country that supplies their manufactured goods or their services, or whatever it may be. Additionally making things, providing services, whatever it may be, develops with practice, into the arts. If we don't ever have that practice we lose the ability, as a nation, to develop those arts.
DiffEq··on Powerful Political Forces Are Aligning Behind Minimum Income
Yet nowhere has this been "field tested" for any length of time. Unless one makes the case that it has been tested in the form of several countries in the 20th century. Places like the the Soviet Union, China, etc. We see that it failed in those places and in Soviet countries it failed fantastically. The fatal flaw in all of this...who is going to pay for it?
DiffEq··on After Cash: All Fun and Games Until Somebody Loses a Bank Account
Not any bank I have ever had dealings with. Smaller local banks tend not to be so fee happy.
DiffEq··on Good Sleep, Good Learning (2012)
Have you ever tried anything with PhGABA in it? The known good source I have found is Biotest's Z-12. From the experience of others using Melatonin will only last so long before it too stops having a noticeable effect. I used Z-12 for a year and it pretty much resolved my issues and now I can sleep 99 percent of the time just as well as when I used to take it...it must have helped reset some Circadian rhythm of some sort because I don't need it anymore to go to sleep or get a good nights sleep.
DiffEq··on You're Eight Times More Likely to Be Killed by a Police Officer Than a Terrorist
So this is the problem with statistics; these statistics apply to the average person. But there is no such thing as an average "real person". For instance MY chances of suicide are zero; and the chances of me being killed by a terrorist are far below the average person because of where I live and where I spend my time; the same goes for being killed by a police officer. This applies to MOST people for at least the "being killed by a police officer category". I think we all know the subset of society that is most prone to being shot by police officers: those that are breaking the law.
DiffEq··on Sex redefined: the idea of two sexes is simplistic
Not being mean here, but purely looked at, these "atypical sexes" are deformities. I don't think it is accurate to call them anything else.
DiffEq··on Why the world's biggest military keeps losing wars
The U.S certainly did pull punches almost the entire war. The Line Backer II operation, which removed those restrictions, force the NV to the table and they were ready to sue for surrender terms...but amazingly the U..S would not let them. In any case everyone agreed to peace and the U.S. went home. After we left the NV broke the peace and invaded South Vietnam again.
DiffEq··on What is the oldest city in the world?
If you aspire to Biblical history and secular, it is the city of Jericho with Damascus a close second.
DiffEq··on I’m an Anti-Braker
The problem here is that not all diseases are the same in terms of risk to health/life or even the ability to infect others. Comparing Smallpox to Polio to the Measles in equal terms is a stretch at best and probably closer to being dishonest. Many people recognize that either wittingly or unwittingly and so getting vaccinated against Measles and Chicken Pox just isn't a high priority. Now to talk about the MMR vaccine: It has had a rough go the last few decades. It was reformulated a couple decades or so ago and the efficacy was massively reduced to around 30% or less if I remember correctly. They went back to the old formulation later but not after a full decade or more of using the new formula that didn't really work. In several of the measles outbreaks of the last decade or so - most, if not all, of those that got the measles had been vaccinated. Of course then everybody blames the anti-vaxers for the outbreaks :(
DiffEq··on Starvation Based Chemotherapy: A Novel Approach for Cancer Treatment [pdf]
Yes, I think "Toughen the cells" as you said is the right way of distilling this article; also note that subjecting yourself to periods of high heat or cold can produce a similar response. The mechanism, in part, is thought to be from what is called "Heat Shock" proteins.

http://en.wikipedia.org/wiki/Heat_shock_protein

As I said before, these proteins are made not just from heat exposure, but from other stress such as fasting and extreme cold exposure. Anyway, I think it is interesting as there is a reasonable amount of ancient literature linking fasting with health(for instance, Isaiah 58:8). Interesting how long science can take to "rediscover" certain basic things the ancients picked up on.

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