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DoubleDerper

646 karma · joined November 29, 2017

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DoubleDerper··on Substack Notes Launched
animated gifs. lots of free tools available. substack probably has staff designers to make it extra pretty.
DoubleDerper··on [dead]
Holy crap those images are fantastically realistic. Thankfully we have Twitter CommunityNotes as a source of truth :-|
DoubleDerper··on The Twitter Files
ranked choice voting can chip away at polarization.
DoubleDerper··on Show HN: This Hacker News Does Not Exist
I disagree with the author. I know he's incredibly successful and right about pretty much everything he's ever said, but I've had some experience in this area and just finished reading through some of the archives and I think his focus is wrong. I'm going to ignore the technical issue and talk about the bigger picture and higher level things than what was said in the blog post. If the OP thinks that the process is most important, it's really about end results. But if he thinks it should be about the end results then he's an idiot for not thinking about the process. I'll weasel in a reference the startup I co-founded even though it's not directly relevant.
DoubleDerper··on Nicotinamide riboside uptake linked to metastasis and NAD+ metabolism
Paging Dr Brad Stanfield. Paging Dr David Sinclair.

Lots of NR and Niacin boosterism that should be treated with skepticism.

The timing of this post is interesting as the FDA has just banned NMN in the US... which seems fortuitous to certain biotech companies & promoters. https://www.youtube.com/watch?v=aalylAdIxS4

DoubleDerper··on IBM unveils 433 qubit quantum computer
i've lost interest in the qubit race.

what can this machine do productively?

DoubleDerper··on Ask HN: What are some of the best documentaries you've seen?
^^^ Thank you! ^^^ Came here to reccommend Connections by James Burke and glad to see someone else has mentioned it. It's a masterpiece of popular science production made better with the grainy film patina of the 70s and 80s.

https://www.youtube.com/watch?v=XetplHcM7aQ

DoubleDerper··on Global Public Opinion in an Era of Democratic Anxiety
Major change in the US begins with ranked-choice voting.
DoubleDerper··on Coinbase lays off around 1,100 employees
Coinbase is notoriously poor at customer service, so this doesn't make sense.

https://news.ycombinator.com/item?id=27653022

DoubleDerper··on The benefits of “low tech” user interfaces
A certain "smart" speaker company replaced their expensive device's single functional button with capacitive touch. The product is worse, now less accessible.
DoubleDerper··on We need a middle class for startups
Seems more like a lucrative "job" than a "business"
DoubleDerper··on Homes in 97% of U.S. cities are overvalued, Moody's says
Relative to which assets?

Stocks? Cars? Forex? IP? Crypto?

Genuinely curious because everything is more expensive than it was before.

If everything is overvalued, then nothing is overvalued [relatively]

DoubleDerper··on I Accidentally Deleted 7TB of Videos Before Going to Production
Don't fire for the mistake. Fire for the inability of someone to own it, cover it up, or point fingers at others.
DoubleDerper··on Mortgage rates just hit 5%. Buying a home has become a lot more expensive
"Luxury" buyers are less sensitive to interest rate increases due to the amount of cash they can deploy.

If more housing stock isn't injected amidst a housing shortage, raising interest rates will disproportionately affects Buyers who really need affordability. Crappy deal.

In cities like Seattle or Austin or Denver, 5% mortgage rates are unlikely to cool the market off in any meaningful way.

DoubleDerper··on “We stand with Ukraine” website badge
Solidarity needs to be visible. Some here will chastise you for virtue signaling and not doing anything else. Choosing a side is a political statement, though, with a value greater than zero.
DoubleDerper··on A $3B bet on finding the fountain of youth
"...anything related to the human body is super-heavily regulated"

In the Western world this is true. Countries with less oversight stand to benefit from regulation arbitrage.

DoubleDerper··on What to Eat and When to Eat for Longevity – Lifespan, David Sinclair EP2
There's no denying that Sinclair has propelled longevity research, but his promotion of certain molecular systems is generating some valid skepticism... https://www.youtube.com/watch?v=e7u6esW3qVw
DoubleDerper··on Ask HN: Who wants to help promote RSS?
The converse is equally true: most people don’t use RSS because the largest content platforms prefer to deliver monetizable algorithmic suggestions.
DoubleDerper··on Samoa Scraps Daylight Saving Time
Is DST a states rights issue in the US? What is the argument FOR keeping DST?
DoubleDerper··on There Is No Reason to Cross the U.S. by Train. But I Did It Anyway. (2019)
One of the luxuries of train travel IS the extra time it takes. Take your time and settle in for a journey versus a cattle-call airport where everyone is angry and cramped inside of a tube 30k feet in the air.
DoubleDerper··on Futarchy: Robin Hanson on prediction markets
Prediction markets will exacerbate the "war on truth," and are illegal in the US, thankfully. "Shorting" is frequently accompanied by disinformation campaigns against a target. It's scary to think about what this will lead to.
DoubleDerper··on Andrew Yang to launch a third party
Ranked-choice voting could be make the most meaningfully positive impact on US democracy in decades. Regardless of your politics.

More messaging, coverage, and support for ranked-choice voting is necessary, and we should all hope to see more of it in coming months/years.

DoubleDerper··on ProtonMail removed “we do not keep any IP logs” from its privacy policy
Consumers relied upon ProtonMail's prominent and concise marketing claim. Consumers who signed up for the service are now in jeopardy, perhaps facing real [legal] injury based on reasonable expectation of not having their IP logged.

The privacy-centric nature of this abuse is unlikely to result in a class-action-type of response, but Caveat Emptor abuses can be dealt with by the marketplace, too.

DoubleDerper··on Dutch cities want to ban property investors in all neighborhoods
"Studies have shown over and over again that investors aren't causing the price increases in the Netherlands"

Source(s), please.

DoubleDerper··on Ostracism
How would this work in modern western society?
DoubleDerper··on Airbnb raises violent crime rates in cities as residents are pushed out
The AirBnb "effect" has directly led to increased home prices. A home turning a profit thus becomes more important than how its guests impact a neighborhood and community. Ignoring or spinning the social costs is a primary goal of Airbnb's PR machine. It has made many neighborhoods more transitory (i.e. less homesteading, more short term rentals). Acknowledge the social costs to community and it's not surprising to read that violent crime rates are trending up where AirBnbs thrive.
DoubleDerper··on Twitter sees jump in govt demands to remove content of reporters, news outlets
From an early age more public investment in STEM, financial literacy, empathic education.
DoubleDerper··on Secret Recordings Reveal How Exxon Lobbyists Manipulate Politicians and Public
Twitter response from Darren Woods, Chairman and CEO of ExxonMobil... “The individuals interviewed were never involved in developing the company’s policy positions on the issues discussed. We condemn the statements and are deeply apologetic for them, including comments regarding interactions with elected officials.”…

https://twitter.com/exxonmobil/status/1410389477214801922

DoubleDerper··on Blood test that finds 50 types of cancer is accurate enough to be rolled out
Shortcut to the source of the technology...

https://grail.com/

DoubleDerper··on ML model can classify sex from retinal photograph, clinicians can't
"EK is a consultant for Google Health. PAK has received speaker fees from Heidelberg Engineering, Topcon, Haag-Streit, Allergan, Novartis and Bayer. PAK has served on advisory boards for Novartis and Bayer, and is a consultant for DeepMind, Roche, Novartis and Apellis. KB has received research grants from Novartis, Bayer. Heidelberg and Roche. KB has received speaker fees from Novartis, Bayer, TopCon, Heidelberg, Allergan, Alimera. KB is a consultant for Novartis, Bayer and Roche. AK is a consultant to Aerie, Allergan, Novartis, Google Health, Reichert and Santen. All other co-authors have no competing interests to declare."

Worth noting.

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