4,612 karma · joined May 24, 2020
Like, here - here's a code that no one will ever solve: ITIWKSMNDIWKD WJSIKWMWMSONQ
Turn that into a sculpture and put it outside the CIA.
No - it's very hard to successfully bet against anything in finance, and VCs and non-public investments are particularly hard. When you go long, you simply buy something and hold it until you decide to sell. If you short, you have to worry about borrowing shares, paying short fees, and having unlimited risk.
How would you even begin to bet against OpenAI specifically? The closest proxy I can think of is shorting NVDA.
There's also nobody whose job it is to make big one-time shorts. Like you said, it's a once in 20-30 years opportunity, so no one builds a hedge fund dedicated to sitting around for decades waiting for that opportunity. There will certainly be exceptions, and maybe they'll make a Big Short 2 about the scrappy underdogs who saw the opening and timed it perfectly. But the vast majority of Wall Street desperately wants the party to continue.
It's unsustainable. I got my PhD 20 years ago, but I would certainly advise my children to avoid it.
Might have more to do with exploiting addiction and ruining lives for profit.
That said, I would also love to see some examples or data, instead of just "it's getting worse".
You seem to be calling for a magical new set of regulations that are just as effective but don't cost as much. That's not going to happen.
I bet most people in the US could tell you in broad strokes who used to live in North America and who conquered them.
Seeing that tau is elevated during development suggests what that role might be. It also suggests that blocking tau entirely in adults might not have any important side effects.