To be honest this feels more like you have an axe to grind with Christianity or its dominance, similar to the people pushing for “BCE/CE” over BC/AD. I don’t know why, but don’t expect the rest of the world to carry that cross for you.
653 karma · joined February 25, 2021
To be honest this feels more like you have an axe to grind with Christianity or its dominance, similar to the people pushing for “BCE/CE” over BC/AD. I don’t know why, but don’t expect the rest of the world to carry that cross for you.
Not sure what the heck you want in terms of validation if not "analysis that supports my point". Are you now criticizing that I've read on this and have data and analysis that agrees? I'm sure if I didn't, you'd come after me for not having that. Double bind sounding ass.
A lot of people seem to have these magic incantations that somehow make LLMs work really well, at the level marketing and investor hype says they do. However, I rarely see that in the real world. I'm not saying this is true for you, but absent vaguely replicable examples that aren't just basic webshit, I find it super hard to believe they're actually this capable.
We all act as we think best. I can try to change how others think. That's about the start and end of it.
Healthcare is one part of the profligate safety net europe has maintained for decades, not the whole thing. Europe has more pensions, more unemployment, more retirement benefits, more childcare, more socialized housing, more of almost every flavor of welfare. They pay for this by shifting the burden of defending themselves to America.
Here's a good and more in-depth analysis: https://foreignpolicy.com/2025/03/04/europe-military-welfare...
It's a hell of a lot more useful than one graph. Please read it.
Get a life dawg.
The short answer is Christianity isn't a utilitarian belief system. While God loves everyone equally, he puts some of us closer together in love: family, friends, neighbors, countrymen. This incurs a greater obligation, plus we ought to love more those who are closer to us.
Sadly, a lot of Christian faiths teach dogma before the underlying reasoning or take a Bible-only approach which I find to be incredibly incomplete. In case your upbringing didn't include much theological reading, I would strongly recommend Civitas Dei and Summa Theologiae; the latter is less explicitly relevant to its definition but probably a better book overall.
I'm unsure what Vance has to do with this. My belief comes from my religious upbringing and (in this case) Saints Augustine and Aquinas. Vance is not a spiritual leader or theologian of any sort.
I think I absorbed much of this when I was pretty young - I had sort of settled on this way of thinking before ever picking up Civitas Dei - but reading and writing on it during my schooling helped me understand why.
There was actually a really good article in the FT of all places on this subject: https://www.ft.com/content/37053b2b-ccda-4ce3-a25d-f1d0f82e7...
The fact that the FT is picking this up should tell us something given its typical perspective. There are two big groups of countries in this situation concerned with keeping russia in check: America and the Euros. The former has less of a direct concern but more ability to do something about it; the former have more concerns but less ability. So we settled on a compromise where each country would contribute a proportion of GDP rather than a dollar figure. This is fair-ish; it's still a huge benefit to the euros, but pretty fair. Yet for decades, they have consistently failed to meet their proportional obligations, instead directing those funds to things like "free healthcare".
Other major reasons they can do this include not having debt from having to finance the rebuilding of their continent themselves.
If your position is "it's his money so none of us should comment", I'd expect equal pushback on people saying "wow I really agree with how he's spending it."
I don't have to argue from the first principles of the EA crowd. Everyone believes in something and I believe they are wrong; your epistemic relativism makes no sense to me. Borderline absurdist.
More importantly, I'm not a utilitarian, and do not subscribe to "effective altruism" or other utilitarian philosophies. At the end of the day it's Gates' money to do with as he wishes and it's my internet account to argue against that as I wish.
You can make a lot of complaints about America but we have, looking back on history, been nicer than any other patron. Other good evidence includes the fact that europe is still standing (paying to rebuild) and her extravagant welfare states of the past decades, subsidized largely by American defense spending.
If you’re suggesting marijuana is also unsafe, I strongly agree. Smoking anything is a risk and more importantly THC is shit for your brain, pro schizophrenic, turns people into lazy fattys, etc. I never have nor will I ever touch THC, absent perhaps light usage for pain if I get cancer or something.
Where I live my high school bio and chem classes gave more than enough foundational knowledge to understand this. It’s not actually that complex and all the remaining info is freely available online.
The risk of molly has little to do with other risk factors besides eg interactions. You fail to understand that risk and damage are the sum of all your risks and damages, not the single highest value. Things stack up.
If your assertion is “frying a little piece of their brains is fine”, I think that’s an extraordinarily reckless thing to do. Adults may have the right to do so, but I will not stop telling them that they are doing so, because most abusers are either unaware or minimize and deny so they can feel good about their abuse.
1. He's talking his book to a certain extent. This is his life's work and he runs a company in this space (though a B corp) so he will have a bias here. That's fine overall, as it may help balance people unfairly biased against psychedelics, but it's worth remembering. I'm not saying this to impugn his character so much as to point out everyone has biases, and someone in his position likely has strong ones, even if partially-founded.
2. He believes an SSRI alleviates negative symptoms, but we don't know it does more than alleviate the comedown. It appears his endpoint was cognitive performance post-use, not long-term damage that may appear once off the SSRI.
3. This doesn't touch the dopaminergic risks of amphetamines, which are substantial.
A few exploratory bits of research into one potential way to alleviate the acute effects post-administration don't translate to an established method to use this in a remotely-safe fashion.
Your suggestions, while interesting, don't remove these risks. Yes, certain types of abuse make it worse: dosing higher, polydrug abuse, hot environments, and dehydration are all ways to damage your brain further. However, use of MDMA in an ideal sense probably still causes some level of damage.
https://pubmed.ncbi.nlm.nih.gov/16472832/
2mg/kg dose, so ~160mg for an adult human. More importantly rat to human is usually a 6ish HED factor so that’d be <30mg. In reality metabolism, brain volume, etc all matter but this is not an even remotely safe drug.
This isn't a "purely theoretical exercise", most of those are established mechanisms of amphetamine toxicity. This isn't "listing possible mechanisms", this is sharing salient info of risks of which possible abusers (given the nature of the thread and discussion so far) should be aware.
I'm sure as heck not "ranting out behaviors that would scare a layperson". Most of what I listed is pretty comprehensible with a grasp of high school chem and bio. Most of the information for this is freely available online. The information we have should scare a layman out of use, and probably someone with a greater background, too.
Whatabout-ing with sleep deprivation or similar doesn't make sense to me either. Did I say that was good or healthy? Bad things stack. Your body doesn't keep a record where it says "you've accumulated 10% damage from an un-fun cause like exhaust or sleep deprivation, so now you get to experience 5% damage from a fun cause like molly." That's just a really weird way of thinking about this.
People are within their moral rights to run the risk but I don't understand this defensiveness that it's somehow a good or smart risk to run for the average case of abuse.
- mitichondrial inhibition
- hyperthermia
- excitotoxicity for DA at least
- hyperthermia speeds up redox cycling of dopamine quinones
- more quinones due to all your dopamine unprotected by vesicles
- metabolic impairment means harder to regenerate NADPH/make glutathione
- probably others I can’t remember at the moment.
You may notice many of these “synergize” in a way that’s particularly bad for the user.
It’s really not worth touching for anyone outside a clinical setting.
2mg/kg dose, so ~160mg for an adult human. More importantly rat to human is usually a 6ish HED factor so that’d be <30mg. In reality metabolism, brain volume, etc all matter but this is not an even remotely safe drug.
Also taking SSRIs near MDMA administration is one of the worst pieces of what is doubtless intended as harm reduction advice I’ve ever seen. You don’t hand people a recipe for serotonin syndrome because of a small scale rat test or two.